Pathophysiology | Unit 5

 Unit 5  Infectious diseases: Meningitis, Typhoid, Leprosy, Tuberculosis Urinary tract infections. Sexually transmitted diseases: AIDS, Syphilis, Gonorrhea Recommended Books (Latest Editions) DOWNLOAD

Biochemistry Notes | Unit 1

 Unit 1  Biomolecules Introduction, classification, chemical nature and biological role of carbohydrate, lipids, nucleic acids, amino acids and proteins. Bioenergetics Concept of free energy, endergonic and exergonic reaction, Relationship between free energy, enthalpy and entropy; Redox potential. Energy rich compounds; classification; biological significances of ATP and cyclic AMP DOWNLOAD

Biochemistry Notes | Unit 2

 Unit 2  Carbohydrate metabolism Glycolysis – Pathway, energetics and significance Citric acid cycle- Pathway, energetics and significance HMP shunt and its significance; Glucose-6-Phosphate dehydrogenase (G6PD) deficiency Glycogen metabolism Pathways and glycogen storage diseases (GSD) Gluconeogenesis- Pathway and its significance Hormonal regulation of blood glucose level and Diabetes mellitus Biological oxidation Electron transport chain (ETC) and … Read more

Biochemistry Notes | Unit 3

 Unit 3  Lipid metabolism β-Oxidation of saturated fatty acid (Palmitic acid) Formation and utilization of ketone bodies; ketoacidosis De novo synthesis of fatty acids (Palmitic acid) Biological significance of cholesterol and conversion of cholesterol into bile acids, steroid hormone and vitamin D Disorders of lipid metabolism: Hypercholesterolemia, atherosclerosis, fatty liver and obesity. Amino acid metabolism … Read more

Biochemistry Notes | Unit 5

 Unit 5  Enzymes Introduction, properties, nomenclature and IUB classification of enzymes Enzyme kinetics (Michaelis plot, Line Weaver Burke plot) Enzyme inhibitors with examples Regulation of enzymes: enzyme induction and repression, allosteric enzymes regulation Therapeutic and diagnostic applications of enzymes and isoenzymes Coenzymes -Structure and biochemical functions DOWNLOAD

Biochemistry Notes | Unit 4

 Unit 4  Nucleic acid metabolism and genetic information transfer Biosynthesis of purine and pyrimidine nucleotides Catabolism of purine nucleotides and Hyperuricemia and Gout disease Organization of mammalian genome Structure of DNA and RNA and their functions DNA replication (semi conservative model) Transcription or RNA synthesis Genetic code, Translation or Protein synthesis and inhibitors DOWNLOAD

Pharmaceutical Organic Chemistry 1 | Unit 1

 Unit 1  Classification, nomenclature and isomerism Classification of Organic Compounds Common and IUPAC systems of nomenclature of organic compounds (up to 10 Carbons open chain and carbocyclic compounds) Structural isomerisms in organic compounds DOWNLOAD

Pharmaceutical Organic Chemistry 1 | Unit 2

 Unit 2  Alkanes*, Alkenes* and Conjugated dienes* SP3 hybridization in alkanes, Halogenation of alkanes, uses of paraffins. Stabilities of alkenes, SP2 hybridization in alkenes E1 and E2 reactions – kinetics, order of reactivity of alkyl halides, rearrangement of carbocations, Saytzeffs orientation and evidences. E1 verses E2 reactions, Factors affecting E1 and E2 reactions. Ozonolysis, electrophilic … Read more

Pharmaceutical Organic Chemistry 1 | Unit 3

 Unit 3  Alkyl halides* SN1 and SN2 reactions – kinetics, order of reactivity of alkyl halides, stereochemistry and rearrangement of carbocations. SN1 versus SN2 reactions, Factors affecting SN1 and SN2 reactions Structure and uses of ethylchloride, Chloroform, trichloroethylene, tetrachloroethylene, dichloromethane, tetrachloromethane and iodoform.   Alcohols* Qualitative tests, Structure and uses of Ethyl alcohol, Methyl alcohol, … Read more

Pharmaceutical Organic Chemistry 1 | Unit 4

 Unit 4  Carbonyl compounds* (Aldehydes and ketones) Nucleophilic addition, Electromeric effect, aldol condensation, Crossed Aldol condensation, Cannizzaro reaction, Crossed Cannizzaro reaction, Benzoin condensation, Perkin condensation, qualitative tests, Structure and uses of Formaldehyde, Paraldehyde, Acetone, Chloral hydrate, Hexamine, Benzaldehyde, Vanilin, Cinnamaldehyde. DOWNLOAD