Unit 1 Biomolecules Introduction, classification, chemical nature and biological role of carbohydrate, lipids, nucleic acids, amino acids and proteins. Bioenergetics Concept of free energy, endergonic and exergonic reaction, Relationship between free energy, enthalpy and entropy; Redox potential. Energy rich compounds; classification; biological significances of ATP and cyclic AMP DOWNLOAD
Unit 2 Carbohydrate metabolism Glycolysis – Pathway, energetics and significance Citric acid cycle- Pathway, energetics and significance HMP shunt and its significance; Glucose-6-Phosphate dehydrogenase (G6PD) deficiency Glycogen metabolism Pathways and glycogen storage diseases (GSD) Gluconeogenesis- Pathway and its significance Hormonal regulation of blood glucose level and Diabetes mellitus Biological oxidation Electron transport chain (ETC) and … Read more
Unit 3 Lipid metabolism β-Oxidation of saturated fatty acid (Palmitic acid) Formation and utilization of ketone bodies; ketoacidosis De novo synthesis of fatty acids (Palmitic acid) Biological significance of cholesterol and conversion of cholesterol into bile acids, steroid hormone and vitamin D Disorders of lipid metabolism: Hypercholesterolemia, atherosclerosis, fatty liver and obesity. Amino acid metabolism … Read more
Unit 5 Enzymes Introduction, properties, nomenclature and IUB classification of enzymes Enzyme kinetics (Michaelis plot, Line Weaver Burke plot) Enzyme inhibitors with examples Regulation of enzymes: enzyme induction and repression, allosteric enzymes regulation Therapeutic and diagnostic applications of enzymes and isoenzymes Coenzymes -Structure and biochemical functions DOWNLOAD
Unit 4 Nucleic acid metabolism and genetic information transfer Biosynthesis of purine and pyrimidine nucleotides Catabolism of purine nucleotides and Hyperuricemia and Gout disease Organization of mammalian genome Structure of DNA and RNA and their functions DNA replication (semi conservative model) Transcription or RNA synthesis Genetic code, Translation or Protein synthesis and inhibitors DOWNLOAD
Imperfect Pharmacy B Pharmacy Notes 2nd SEMESTER BIOCHEMISTRY UNIT 1 Biomolecules Introduction, classification, chemical nature and biological role of carbohydrate, lipids, nucleic acids, amino acids and proteins. Bioenergetics Concept of free energy, endergonic and exergonic reaction, Relationship between free energy, enthalpy and entropy; Redox potential. Energy rich compounds; classification; biological significances of ATP and … Read more