Pharmaceutical Organic Chemistry 2 | Unit 1

 Unit 1 

Benzene and its derivatives

  • Analytical, synthetic and other evidences in the derivation of structure of benzene, Orbital picture, resonance in benzene, aromatic characters, Huckel’s rule
  • Reactions of benzene – nitration, sulphonation, halogenationreactivity, Friedelcrafts alkylation- reactivity, limitations, Friedelcrafts acylation.
  • Substituents, effect of substituents on reactivity and orientation of mono substituted benzene compounds towards electrophilic substitution reaction
  • Structure and uses of DDT, Saccharin, BHC and Chloramine